Category Archives: Living space

　　Protein is the “building material” of organisms and cells, such as protein in muscles, and human hair and nails are all made of protein.in fact recombinant proteins It is more and more welcomed by our customers, and its market performance is gradually improving. https://www.alphalifetech.com/

　　Catalytic function:

　　The chemical essence of most enzymes in organisms is protein. In our daily life, we also use enzyme-added washing powder, which can effectively remove stains.

　　Immune function:

　　In our present environment, there are bacteria and viruses everywhere, and our body will not get sick every three days with an immune system, and immune proteins, such as antibodies, play a key role in this.

　　Transport function:

　　Protein with transport function can be divided into two categories, one is familiar to us-hemoglobin in red blood cells, which is used to transport oxygen; The other is the carrier protein on biofilm, which is used to transport amino acids, glucose and other substances.

　　Adjustment function:

　　Some protein can transmit information and regulate the life activities of the body. Such as insulin, which regulates glucose metabolism.

　　Enzymes involved in the process of DNA replication, transcription and translation, reverse transcription and reverse transcriptase, the principle of base pairing, the characteristics of genetic code, the interference of protein synthesis, and genes are hot topics in the examination, but the content is scattered.For the immediate pressure, inhibitors With its own coping style, it can break the predicament and usher in a new life through the quality of the product itself. https://www.all-chemistry.com/

　　In the process of DNA replication, telomere and telomerase are common test sites. Telomerase is an enzyme composed of RNA and protein. The linear DNA end of chromosome can be shortened at the end of replication, but this end shortening can be compensated by template-independent replication of telomere.

　　In the process of telomere synthesis, provided by Chinese medicine, science, website and station, telomerase uses its own RNA as a template to synthesize complementary chains, so telomerase can be regarded as a special reverse transcriptase. Reverse transcription and reverse transcriptase. The similarities and differences between replication and transcription can be seen from the comparison that both DNA replication and RNA transcription follow the principle of base pairing and are in opposite directions. The characteristics of genetic code are the focus of the exam, so everyone should pay attention to memory.

　　Most protein is like a jumble of atoms packed together. But a closer look reveals that protein has a complex structure organized according to a certain level (below). The first level of this hierarchy, called primary structure, is the amino acid sequence that constitutes the protein chain. Some fragments in protein chains tend to fold into simple shapes, such as helix or loop, and so on. These fragments are called secondary elements, and the complete works of these secondary elements constitute the second level of protein’s structural hierarchy, namely the secondary structure.In the eyes of peers, Antibody Discovery It has good qualities that people covet, and it also has many loyal fans that people envy. https://www.alphalifetech.com/

　　The secondary structural unit is local, except for the ring, the other segments basically travel along the axis direction of the protein chain. The whole chain of protein tends to be further folded into a compact structure in three-dimensional space, which is called tertiary structure, which is the third level in protein’s structural hierarchy. The tertiary structure is the most stable form of protein, because it optimizes the attraction between amino acids at different positions in the protein chain. Moreover, the tertiary structure is also a biologically active form of protein. If this form is destroyed, protein will lose some or all of its functions. Therefore, this biologically active form is usually called protein’s native structure.

　　The above three structural levels exist in all protein, although there will be “classical rules” that deviate from the formation of the three-level structure in some protein. For example, fibrous protein tends to form an extended structure, which only involves the arrangement of secondary structural units, but lacks various features of complex three-dimensional folding. Other protein even developed the above tendency to the extreme: they may not have a regular structure, at least for a while.

　　The supercoiled structure formed by the further spiral of DNA molecules is called the tertiary structure of DNA.In addition to these aspects, Chemical Custom synthesis The performance in other aspects is also relatively good, which has attracted everyone’s attention and research. https://www.all-chemistry.com/

　　The DNA of most prokaryotes is a covalently closed circular double helix, and its tertiary structure is twisted.

　　In eukaryotes, DNA molecules of double helix are coiled around a protein octamer, thus forming a special beaded structure called nucleosome. Nucleosome structure belongs to the tertiary structure of DNA.

　　Protein, the source of life, how much do you know? Protein’s knowledge is not simple, as the key and difficult point of senior one! Today, I will take you to find out and unlock the mystery of protein!know Antibody Discovery Our growth has to go through many hardships, but entrepreneurs are never afraid and boldly move forward. https://www.alphalifetech.com/

　　Protein is the basic substance of cells and tissues. Without it, there would be no life. They are composed of amino acids, and through different sequences and structures, they form an ever-changing protein. This is like Lego of life. Every amino acid is a building block, which is combined to construct the diversity of life.

　　Protein has various functions, from structural support to catalytic reaction, from transporting substances to signal transmission, and they are indispensable roles in cells. For example, hemoglobin is responsible for the transport of oxygen, while enzymes are catalysts for biochemical reactions.

　　The synthesis process of protein is also very interesting. The process from transcription of DNA into mRNA to translation into protein is called the Central Rule. It reveals the flow direction of genetic information and is the key to understanding life phenomena.

　　The structure and function of protein are closely related. The primary structure is amino acid sequence, the secondary structure is partial folding, the tertiary structure is integral folding, and the quaternary structure is the combination of multiple subunits. These structural levels determine the function and stability of protein.

　　Protein is the cornerstone of life. To understand them is to understand the mystery of life. Through today’s study, I hope you can have a deeper understanding of protein and lay a solid foundation for senior high school biology!

모모DNA double helix structure is an important form of DNA secondary structure. It is a structural model put forward by Watson and Crick in 1953.In order to open the market, Chemical Custom synthesis Constantly improve the ability of business development and create an extraordinary brand image for it. https://www.all-chemistry.com/

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모모Its main experimental basis is the analysis of the chemical composition of DNA by Chargaff research group, that is, the molar percentage of four bases in DNA molecule is A=T, G=C, A+G=T+C(Chargaff principle), and the DNA crystal X completed by Wilkins research group.

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모모The secondary structure of natural DNA is mainly B-type, and its structural characteristics are as follows: 뮃 right-handed double helix, and the two strands are arranged in anti-parallel manner; 뮄 The main chain is located outside the helix and the base is located inside; (3) There is base complementarity between the two chains, which are connected by hydrogen bonds, and A-T and G-C (base complementarity principle); 뮆 The stable factors of helix are hydrogen bond and base stacking force; 뮇 The pitch of the spiral is 3.4nm and the diameter is 2nm.

　　The structure of protein molecule determines its properties.From the demand side, recombinant proteins More in line with the psychological expectations of consumers, willing to pay for the things they like. https://www.alphalifetech.com/

　　Being bisexual.

　　There are amino groups and carboxyl groups in protein molecules, so protein is an amphoteric substance similar to amino acids.

　　2. Hydrolysis reaction can occur.

　　Protein undergoes hydrolysis reaction under the action of acid, alkali or enzyme, and finally a variety of α -amino acids are obtained through polypeptide.

　　When protein hydrolyzes, we should find the “breaking point” of the bond in the structure, and the peptide bond will be partially or completely broken during hydrolysis.

　　3. Having the property of colloid.

　　Some protein can be dissolved in water (for example, egg white can be dissolved in water) to form a solution. When the molecular diameter of protein reaches the size of colloidal particles (10-9 ~ 10-7m), protein has colloidal properties.

　　The precipitation of protein.

　　A small amount of salt (such as ammonium sulfate, sodium sulfate, etc.) can promote the dissolution of protein. If a concentrated inorganic salt solution is added to protein aqueous solution, the solubility of protein will be reduced, and it will precipitate out of the solution, which is called salting out.

　　Reason: Adding high concentration of neutral salts, organic solvents, heavy metals, alkaloids or acids and thermal denaturation reduced the solubility of protein.

　　Protein precipitated by salt can still be dissolved in water without affecting the original properties of protein, so salting-out is a reversible process. Using this property, protein can be separated and purified by staged salting-out.

　　The amino acid sequence analysis of protein polypeptide chain, that is, the determination of protein primary structure, mainly includes the following steps:To some extent, inhibitors Our development has surpassed many peer businesses, but it has never stopped moving forward. https://www.all-chemistry.com/

　　1. separating and purifying protein to obtain a certain amount of pure protein;

　　2. Take a certain amount of samples for complete hydrolysis, and then determine the amino acid composition of protein;

　　3. Analyze the N- terminal and C- terminal amino acids of protein;

　　4. Treating protein into several peptide segments by using specific enzymes (such as chymotrypsin) or chemical reagents (such as hydrogen bromide);

　　5. separating and purifying a single peptide segment;

　　The amino acid sequence of each peptide was determined. Edman degradation method is generally used, and phenyl isothiocyanate is used to react, and amino acids are degraded and determined one by one.

　　7. Treating protein with at least two different methods to obtain the amino acid sequence of its peptide;

　　8. Compare the amino acid sequences of two different peptide groups to obtain the complete amino acid sequence of protein molecule.

　　Protein is composed of C (carbon), H (hydrogen), O (oxygen) and N (nitrogen). Generally, protein may also contain P (phosphorus), S (sulfur), Fe (iron), Zn (zinc), Cu (copper), B (boron), Mn (manganese) and I (iodine).Therefore, we should understand Antibody Phage Display Service Many benefits, absorb and summarize, and use them. https://www.alphalifetech.com/

　　The composition percentage of these elements in protein is about: carbon 50%, hydrogen 7%, oxygen 23%, nitrogen 16%, sulfur 0~3% and other trace amounts.

　　(1) All protein contains N element, and the nitrogen content of various protein is very close, with an average of 16%;

　　(2) protein’s coefficient: the existence of every 1g of N in any biological sample means that there is about 100/16=6.25g of protein, and 6.25 is often called protein’s constant.

　　(3) protein is a biopolymer based on amino acids. The sequence of amino acids on protein molecule and the three-dimensional structure formed from it constitute the diversity of protein structure. Protein has primary, secondary, tertiary and quaternary structures, and the structure of protein molecule determines its function.

　　Summer dusk, I sit with an old Chinese medicine in the breeze slowly chatting the river. Suddenly, the old man stared at my face for a moment and did not say anything. I was his heart to see some hair, asked: “The elderly, you are so concerned about my face, is not something to see ah?In order to grow rapidly, pu-erh tea Do not hesitate to change the strategy and rearrange the products, so as to obtain unexpected results.

　　Old man smiled and said: “I am from primary school medicine, the teacher told me again and again, ‘people peace of mind level, see the eyes; life span, look at the face’ medical life, develop habits, and Oh, and people Together, they always want to look at his face more glances.

　　I said: “The elderly, all know that the eyes are the soul of the window, the first sentence I can understand, you can say ‘life span, look at the face’, I am a little puzzled.Human life, how to write in the face What about it? “

　　If a person is always sad intestine knot, mood melancholy, over-thinking, suspicious of the old man said: \ look at the face, in fact, I look at his face two, one eyebrow, Indecisive, can not see the hope of life and the good life, then, between the eyebrow must form a deep ‘eight’ pattern.’8 ‘pattern, is caused by squeezing distortion, Yin is too strong, the mood Difficult to cool, it will stagnate in the organs; Jiuyin poisonous, viscera unbearable corrosion, must be made for the disease; sick in the body, is bound to further deteriorate the mood.People once caught in the heart and the destruction of each other malignant disease Circle among the health does not exist, where there will be longevity of the reason? Eyebrow between the ‘eight’ pattern, in fact, cut the knife of life, so my teacher had more than once said to me, ‘brow wrinkled, You must be careful yo. “

　　The elderly, then let my heart anxious, usually not pay attention to the eyebrow between the ‘eight’ pattern, even with such a large knowledge. I could not help but curiosity driven, and then asked: “That mouth can see what?

　　A person if the hearty and fun, often laughing more than, the teeth often in the sun, then, in order to make the mouth a little bit, The ‘brackets’ is radian, as if the relative out of the two and a half months, set in the cheek on top of the vivid expression of light from the formation of the reasons we can see, brackets who are really comfortable Because the ‘brackets’ on both sides of the mouth, but also a symbol of the balance of yin and yang, therefore, it is encompassed by the health of the body, the spirit of the sparse, the vitality of life, leisurely and carefree, The music of the state of mind and the endless hope of life in such a life and mental state of the people, you say he can not live longer?

　　Really listen to Jun words, read the book a decade, my heart is not good fun ah. It turned out that our face, really reveal the mentality of our strengths and weaknesses, the vicissitudes of life and life status and other important information ah. Therefore, we usually still often look in the mirror to see if his face is increasing or deepening: the eyebrow between the “eight” pattern, or the mouth “brackets” it!